Biomolecules

Classes of Biochemical Compounds

Biochemical compounds make up the cells and tissues of living things. They are also involved in all life processes. Given their diversity of functions, it’s not surprising that there are millions of different biochemical compounds. Even so, all biochemical compounds can be grouped into just four main classes: carbohydrates, proteins, lipids, and nucleic acids.

Glucose

Carbohydrates

Carbohydrates are biochemical compounds that include sugar, starch, glycogen, and cellulose. Sugars are simple carbohydrates with relatively small molecules. Glucose is the smallest of all the sugar molecules with its chemical formula of C6H12O6. This means that a molecule of glucose contains 6 atoms of carbon, 12 atoms of hydrogen, and 6 atoms of oxygen. Plants and some other organisms make glucose in the process of photosynthesis. Living things that cannot make glucose can obtain it by consuming plants or organisms that consume plants.

Starches are complex carbohydrates. They are polymers of glucose. Starches contain hundreds of glucose monomers. Plants make starches to store extra glucose. Consumers can get starches by eating plants. Our digestive system breaks down starches to sugar, which our cells use for energy. Like other animals, we store any extra glucose as the complex carbohydrate called glycogen. Glycogen is also a polymer of glucose.

Cellulose is another complex carbohydrate found in plants that is a polymer of glucose. Cellulose molecules bundle together to form long, tough fibers. Cellulose is the most abundant biochemical compound. It makes up the cell walls of plants and gives support to stems and tree trunks

Cellulose

Lactose

Proteins
Proteins are biochemical compounds that consist of one or more chains of small molecules called amino acids. Amino acids are the monomers of proteins. There are only about 20 different amino acids. The sequence of amino acids in chains and the number of chains in a protein determine the protein’s shape. Shapes may be very complex. The shape of a protein determines its function. Proteins have many different functions. For example, proteins:

make up muscle tissues.
speed up chemical reactions in cells.
regulate life processes.
help defend against infections.
transport materials around the body in the blood.

Hemoglobin is an example of a transport protein in the blood. The heme parts of a hemoglobin molecule bind with oxygen. Each red blood cell has hundreds of hemoglobin molecules and each hemoglobin molecule can carry up to four oxygen molecules. This is how oxygen is carried in the blood to cells throughout the body.

Amino Acid - Isoleucine

Amino Acid - Glycine

Amino Acid - Arginine

Lipids
Lipids are biochemical compounds that living things use to store energy and make cell membranes. Types of lipids include fats, oils, and phospholipids.

Fats are solid lipids that animals use to store energy. Examples of fats include butter and the fat in meat.
Oils are liquid lipids that plants use to store energy. Examples of oils include olive oil and corn oil.
Phospholipids contain the element phosphorus. They make up the cell membranes of living things.

Lipids are made of long chains consisting almost solely of carbon and hydrogen. These long chains are called fatty acids. Fatty acids may be saturated or unsaturated.

In saturated fatty acids, carbon atoms are bonded to as many hydrogen atoms as possible. In other words, the carbon atoms are saturated with hydrogen. Saturated fatty acids are found in fats.
In unsaturated fatty acids, some carbon atoms are not bonded to as many hydrogen atoms as possible. Instead, they share double bonds with other carbon atoms. Unsaturated fatty acids are found in oils.

Saturated & unsaturated fatty acids

Nucleic Acids
Nucleic acids are biochemical compounds that include RNA (ribonucleic acid) and DNA (deoxyribonucleic acid). Nucleic acids consist of chains of small molecules called nucleotides. Nucleotides are the monomers of nucleic acids.
Each nucleotide consists of:

a phosphate group, which contains phosphorus and oxygen.
a sugar, which is deoxyribose in DNA and ribose in RNA.
one of four nitrogen-containing bases. (A base is a compound that is not neither acidic nor neutral.) In DNA, the bases are adenine, thymine, guanine, and cytosine. RNA has the base uracil instead of thymine, but the other three bases are the same.

RNA consists of just one chain of nucleotides. DNA consists of two chains. Nitrogen bases on the two chains of DNA form bonds with each other. The bonded bases are called base pairs. Bonds form only between adenine and thymine, and between guanine and cytosine. They hold together the two chains of DNA and give it its characteristic double helix, or spiral, shape. Sugars and phosphate groups form the “backbone” of each chain of DNA. Determining the structure of DNA was a huge scientific breakthrough.
DNA stores genetic information in the cells of all living things. It contains the genetic code. This is the code that instructs cells how to make proteins. The instructions are encoded in the sequence of nitrogen bases in DNA’s nucleotide chains. RNA copies and interprets the genetic code in DNA.

DNA nucleotide

RNA nucleotide

Link to Readings

This link has everything you need to know about the four main biomolecules. I highly recommend you read each page.

This portion of the course is where we are going to go much further in depth than the regular biology course. Understanding biomolecules means being able to explain chemical bonding, reading shorthand chemical structure diagrams, and learning names of functional groups. I recommend you spend a lot of time outside of class reading around this subject because it is going to be difficult.